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International science careers survey: staying a step ahead.

New biotechnology

Rindoks A, Daniłowicz E.
PMID: 18775523
N Biotechnol. 2008 Oct-Dec;25(2):125. doi: 10.1016/j.nbt.2008.08.008. Epub 2008 Aug 27.

No abstract available.

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Rindoks A, Daniłowicz E. International science careers survey: staying a step ahead. N Biotechnol. 2008;25(2):125doi: 10.1016/j.nbt.2008.08.008.
Rindoks, A., & Daniłowicz, E. (2008). International science careers survey: staying a step ahead. New biotechnology, 25(2), 125. https://doi.org/10.1016/j.nbt.2008.08.008
Rindoks, Aimee, and Daniłowicz, Emilia. "International science careers survey: staying a step ahead." New biotechnology vol. 25,2 (2008): 125. doi: https://doi.org/10.1016/j.nbt.2008.08.008
Rindoks A, Daniłowicz E. International science careers survey: staying a step ahead. N Biotechnol. 2008 Oct-Dec;25(2):125. doi: 10.1016/j.nbt.2008.08.008. Epub 2008 Aug 27. PMID: 18775523.
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Editorial introduction for the Synthetic Biology thematic issue.

New biotechnology

Cole J.
PMID: 24631757
N Biotechnol. 2014 Dec 25;31(6):525-7. doi: 10.1016/j.nbt.2014.02.012. Epub 2014 Mar 12.

Synthetic biology strives to develop organisms, enzymes, and processes that do not occur naturally to solve specific biotechnological problems. Often this requires genetic engineering to change a natural process, or to combine genes from different sources to create new...

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Cole J. Editorial introduction for the Synthetic Biology thematic issue. N Biotechnol. 2014;31(6):525-7doi: 10.1016/j.nbt.2014.02.012.
Cole, J. (2014). Editorial introduction for the Synthetic Biology thematic issue. New biotechnology, 31(6), 525-7. https://doi.org/10.1016/j.nbt.2014.02.012
Cole, Jeff. "Editorial introduction for the Synthetic Biology thematic issue." New biotechnology vol. 31,6 (2014): 525-7. doi: https://doi.org/10.1016/j.nbt.2014.02.012
Cole J. Editorial introduction for the Synthetic Biology thematic issue. N Biotechnol. 2014 Dec 25;31(6):525-7. doi: 10.1016/j.nbt.2014.02.012. Epub 2014 Mar 12. PMID: 24631757.
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Personalised medicine in 2012: editorial to the special issue of New Biotechnology on "molecular diagnostics & personalised medicine".

New biotechnology

Desiere F, Romano Spica V.
PMID: 22504736
N Biotechnol. 2012 Sep 15;29(6):611-2. doi: 10.1016/j.nbt.2012.03.010. Epub 2012 Apr 05.

This special issue of New Biotechnology is focused on molecular diagnostics and personalised medicine and appears at an epochal moment in the development of the field. The practice of medicine is taking a significant and irrevocable turn towards personalisation,...

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Desiere F, Romano Spica V. Personalised medicine in 2012: editorial to the special issue of New Biotechnology on "molecular diagnostics & personalised medicine". N Biotechnol. 2012;29(6):611-2doi: 10.1016/j.nbt.2012.03.010.
Desiere, F., & Romano Spica, V. (2012). Personalised medicine in 2012: editorial to the special issue of New Biotechnology on "molecular diagnostics & personalised medicine". New biotechnology, 29(6), 611-2. https://doi.org/10.1016/j.nbt.2012.03.010
Desiere, Frank, and Romano Spica, Vincenzo. "Personalised medicine in 2012: editorial to the special issue of New Biotechnology on "molecular diagnostics & personalised medicine"." New biotechnology vol. 29,6 (2012): 611-2. doi: https://doi.org/10.1016/j.nbt.2012.03.010
Desiere F, Romano Spica V. Personalised medicine in 2012: editorial to the special issue of New Biotechnology on "molecular diagnostics & personalised medicine". N Biotechnol. 2012 Sep 15;29(6):611-2. doi: 10.1016/j.nbt.2012.03.010. Epub 2012 Apr 05. PMID: 22504736.
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Corrigendum to "The pre-analytical phase of liquid biopsy" [New Biotechnol. 55, 25 March 2020, 19-29].

New biotechnology

Salvianti F, Gelmini S, Costanza F, Mancini I, Sonnati G, Simi L, Pazzagli M, Pinzani P.
PMID: 31761728
N Biotechnol. 2020 May 25;56:149. doi: 10.1016/j.nbt.2019.10.011. Epub 2019 Nov 21.

No abstract available.

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Salvianti F, Gelmini S, Costanza F, et al. Corrigendum to "The pre-analytical phase of liquid biopsy" [New Biotechnol. 55, 25 March 2020, 19-29]. N Biotechnol. 2019;56:149doi: 10.1016/j.nbt.2019.10.011.
Salvianti, F., Gelmini, S., Costanza, F., Mancini, I., Sonnati, G., Simi, L., Pazzagli, M., & Pinzani, P. (2020). Corrigendum to "The pre-analytical phase of liquid biopsy" [New Biotechnol. 55, 25 March 2020, 19-29]. New biotechnology, 56149. https://doi.org/10.1016/j.nbt.2019.10.011
Salvianti, F, et al. "Corrigendum to "The pre-analytical phase of liquid biopsy" [New Biotechnol. 55, 25 March 2020, 19-29]." New biotechnology vol. 56 (2020): 149. doi: https://doi.org/10.1016/j.nbt.2019.10.011
Salvianti F, Gelmini S, Costanza F, Mancini I, Sonnati G, Simi L, Pazzagli M, Pinzani P. Corrigendum to "The pre-analytical phase of liquid biopsy" [New Biotechnol. 55, 25 March 2020, 19-29]. N Biotechnol. 2020 May 25;56:149. doi: 10.1016/j.nbt.2019.10.011. Epub 2019 Nov 21. PMID: 31761728.
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In vivo evolution of lactic acid hyper-tolerant Clostridium thermocellum.

New biotechnology

Mazzoli R, Olson DG, Concu AM, Holwerda EK, Lynd LR.
PMID: 34915174
N Biotechnol. 2022 Mar 25;67:12-22. doi: 10.1016/j.nbt.2021.12.003. Epub 2021 Dec 13.

Lactic acid (LA) has several applications in the food, cosmetics and pharmaceutical industries, as well as in the production of biodegradable plastic polymers, namely polylactides. Industrial production of LA is essentially based on microbial fermentation. Recent reports have shown...

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Mazzoli R, Olson DG, Concu AM, et al. In vivo evolution of lactic acid hyper-tolerant Clostridium thermocellum. N Biotechnol. 2021;67:12-22doi: 10.1016/j.nbt.2021.12.003.
Mazzoli, R., Olson, D. G., Concu, A. M., Holwerda, E. K., & Lynd, L. R. (2022). In vivo evolution of lactic acid hyper-tolerant Clostridium thermocellum. New biotechnology, 6712-22. https://doi.org/10.1016/j.nbt.2021.12.003
Mazzoli, Roberto, et al. "In vivo evolution of lactic acid hyper-tolerant Clostridium thermocellum." New biotechnology vol. 67 (2022): 12-22. doi: https://doi.org/10.1016/j.nbt.2021.12.003
Mazzoli R, Olson DG, Concu AM, Holwerda EK, Lynd LR. In vivo evolution of lactic acid hyper-tolerant Clostridium thermocellum. N Biotechnol. 2022 Mar 25;67:12-22. doi: 10.1016/j.nbt.2021.12.003. Epub 2021 Dec 13. PMID: 34915174.
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Targeted mutagenesis in plants using Beet curly top virus for efficient delivery of CRISPR/Cas12a components.

New biotechnology

Eini O, Schumann N, Niessen M, Varrelmann M.
PMID: 34896246
N Biotechnol. 2022 Mar 25;67:1-11. doi: 10.1016/j.nbt.2021.12.002. Epub 2021 Dec 08.

Genome editing using CRISPR/Cas is rapidly being developed for gene targeting in eukaryotes including plants. However, gene targeting by homology-directed DNA recombination (HDR) is an infrequent event compared to the dominant DNA repair by non-homologous end-joining. Another bottleneck is...

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Eini O, Schumann N, Niessen M, et al. Targeted mutagenesis in plants using Beet curly top virus for efficient delivery of CRISPR/Cas12a components. N Biotechnol. 2021;67:1-11doi: 10.1016/j.nbt.2021.12.002.
Eini, O., Schumann, N., Niessen, M., & Varrelmann, M. (2022). Targeted mutagenesis in plants using Beet curly top virus for efficient delivery of CRISPR/Cas12a components. New biotechnology, 671-11. https://doi.org/10.1016/j.nbt.2021.12.002
Eini, Omid, et al. "Targeted mutagenesis in plants using Beet curly top virus for efficient delivery of CRISPR/Cas12a components." New biotechnology vol. 67 (2022): 1-11. doi: https://doi.org/10.1016/j.nbt.2021.12.002
Eini O, Schumann N, Niessen M, Varrelmann M. Targeted mutagenesis in plants using Beet curly top virus for efficient delivery of CRISPR/Cas12a components. N Biotechnol. 2022 Mar 25;67:1-11. doi: 10.1016/j.nbt.2021.12.002. Epub 2021 Dec 08. PMID: 34896246.
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Applicability and information value of biocalorimetry for the monitoring of fungal solid-state fermentation of lignocellulosic agricultural by-products.

New biotechnology

Duong HL, Paufler S, Harms H, Maskow T, Schlosser D.
PMID: 34767975
N Biotechnol. 2021 Nov 09;66:97-106. doi: 10.1016/j.nbt.2021.11.001. Epub 2021 Nov 09.

The applicability of biocalorimetry for monitoring fungal conversion of lignocellulosic agricultural by-products during solid-state fermentation (SSF) was substantiated through linking the non-invasive measurement of metabolic heat fluxes to conventional invasive determination of fungal activity (growth, substrate degradation, enzyme activity)...

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Duong HL, Paufler S, Harms H, et al. Applicability and information value of biocalorimetry for the monitoring of fungal solid-state fermentation of lignocellulosic agricultural by-products. N Biotechnol. 2021;66:97-106doi: 10.1016/j.nbt.2021.11.001.
Duong, H. L., Paufler, S., Harms, H., Maskow, T., & Schlosser, D. (2021). Applicability and information value of biocalorimetry for the monitoring of fungal solid-state fermentation of lignocellulosic agricultural by-products. New biotechnology, 6697-106. https://doi.org/10.1016/j.nbt.2021.11.001
Duong, Hieu Linh, et al. "Applicability and information value of biocalorimetry for the monitoring of fungal solid-state fermentation of lignocellulosic agricultural by-products." New biotechnology vol. 66 (2021): 97-106. doi: https://doi.org/10.1016/j.nbt.2021.11.001
Duong HL, Paufler S, Harms H, Maskow T, Schlosser D. Applicability and information value of biocalorimetry for the monitoring of fungal solid-state fermentation of lignocellulosic agricultural by-products. N Biotechnol. 2021 Nov 09;66:97-106. doi: 10.1016/j.nbt.2021.11.001. Epub 2021 Nov 09. PMID: 34767975.
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Fed-batch production assessment of a tetravalent bispecific antibody: A case study on piggyBac stably transfected HEK293 cells.

New biotechnology

Napoleone A, Laurén I, Linkgreim T, Dahllund L, Persson H, Andersson O, Olsson A, Hultqvist G, Frank P, Hall M, Morrison A, Andersson A, Lord M, Mangsbo S.
PMID: 34273575
N Biotechnol. 2021 Nov 25;65:9-19. doi: 10.1016/j.nbt.2021.07.002. Epub 2021 Jul 15.

The transition from preclinical biological drug development into clinical trials requires an efficient upscaling process. In this context, bispecific antibody drugs are particularly challenging due to their propensity to form aggregates and generally produce low titers. Here, the upscaling...

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Napoleone A, Laurén I, Linkgreim T, et al. Fed-batch production assessment of a tetravalent bispecific antibody: A case study on piggyBac stably transfected HEK293 cells. N Biotechnol. 2021;65:9-19doi: 10.1016/j.nbt.2021.07.002.
Napoleone, A., Laurén, I., Linkgreim, T., Dahllund, L., Persson, H., Andersson, O., Olsson, A., Hultqvist, G., Frank, P., Hall, M., Morrison, A., Andersson, A., Lord, M., & Mangsbo, S. (2021). Fed-batch production assessment of a tetravalent bispecific antibody: A case study on piggyBac stably transfected HEK293 cells. New biotechnology, 659-19. https://doi.org/10.1016/j.nbt.2021.07.002
Napoleone, Antonino, et al. "Fed-batch production assessment of a tetravalent bispecific antibody: A case study on piggyBac stably transfected HEK293 cells." New biotechnology vol. 65 (2021): 9-19. doi: https://doi.org/10.1016/j.nbt.2021.07.002
Napoleone A, Laurén I, Linkgreim T, Dahllund L, Persson H, Andersson O, Olsson A, Hultqvist G, Frank P, Hall M, Morrison A, Andersson A, Lord M, Mangsbo S. Fed-batch production assessment of a tetravalent bispecific antibody: A case study on piggyBac stably transfected HEK293 cells. N Biotechnol. 2021 Nov 25;65:9-19. doi: 10.1016/j.nbt.2021.07.002. Epub 2021 Jul 15. PMID: 34273575.
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The PAR promoter expression system: Modified lac promoters for controlled recombinant protein production in Escherichia coli.

New biotechnology

Hothersall J, Godfrey RE, Fanitsios C, Overton TW, Busby SJW, Browning DF.
PMID: 33984501
N Biotechnol. 2021 Sep 25;64:1-8. doi: 10.1016/j.nbt.2021.05.001. Epub 2021 May 10.

Many commonly used bacterial promoters employed for recombinant protein production (RPP) in Escherichia coli are capable of high-level protein expression. However, such promoter systems are often too strong, being ill suited for expressing proteins that are difficult to fold,...

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Hothersall J, Godfrey RE, Fanitsios C, et al. The PAR promoter expression system: Modified lac promoters for controlled recombinant protein production in Escherichia coli. N Biotechnol. 2021;64:1-8doi: 10.1016/j.nbt.2021.05.001.
Hothersall, J., Godfrey, R. E., Fanitsios, C., Overton, T. W., Busby, S. J. W., & Browning, D. F. (2021). The PAR promoter expression system: Modified lac promoters for controlled recombinant protein production in Escherichia coli. New biotechnology, 641-8. https://doi.org/10.1016/j.nbt.2021.05.001
Hothersall, Joanne, et al. "The PAR promoter expression system: Modified lac promoters for controlled recombinant protein production in Escherichia coli." New biotechnology vol. 64 (2021): 1-8. doi: https://doi.org/10.1016/j.nbt.2021.05.001
Hothersall J, Godfrey RE, Fanitsios C, Overton TW, Busby SJW, Browning DF. The PAR promoter expression system: Modified lac promoters for controlled recombinant protein production in Escherichia coli. N Biotechnol. 2021 Sep 25;64:1-8. doi: 10.1016/j.nbt.2021.05.001. Epub 2021 May 10. PMID: 33984501.
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Accelerostat study in conventional and microfluidic bioreactors to assess the key role of residual glucose in the dimorphic transition of Yarrowia lipolytica in response to environmental stimuli.

New biotechnology

Lesage J, Timoumi A, Cenard S, Lombard E, Lee HLT, Guillouet SE, Gorret N.
PMID: 34058397
N Biotechnol. 2021 Sep 25;64:37-45. doi: 10.1016/j.nbt.2021.05.004. Epub 2021 May 29.

Yarrowia lipolytica, with a diverse array of biotechnological applications, is able to grow as ovoid yeasts or filamentous hyphae depending on environmental conditions. This study has explored the relationship between residual glucose levels and dimorphism in Y. lipolytica. Under...

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Lesage J, Timoumi A, Cenard S, et al. Accelerostat study in conventional and microfluidic bioreactors to assess the key role of residual glucose in the dimorphic transition of Yarrowia lipolytica in response to environmental stimuli. N Biotechnol. 2021;64:37-45doi: 10.1016/j.nbt.2021.05.004.
Lesage, J., Timoumi, A., Cenard, S., Lombard, E., Lee, H. L. T., Guillouet, S. E., & Gorret, N. (2021). Accelerostat study in conventional and microfluidic bioreactors to assess the key role of residual glucose in the dimorphic transition of Yarrowia lipolytica in response to environmental stimuli. New biotechnology, 6437-45. https://doi.org/10.1016/j.nbt.2021.05.004
Lesage, Julie, et al. "Accelerostat study in conventional and microfluidic bioreactors to assess the key role of residual glucose in the dimorphic transition of Yarrowia lipolytica in response to environmental stimuli." New biotechnology vol. 64 (2021): 37-45. doi: https://doi.org/10.1016/j.nbt.2021.05.004
Lesage J, Timoumi A, Cenard S, Lombard E, Lee HLT, Guillouet SE, Gorret N. Accelerostat study in conventional and microfluidic bioreactors to assess the key role of residual glucose in the dimorphic transition of Yarrowia lipolytica in response to environmental stimuli. N Biotechnol. 2021 Sep 25;64:37-45. doi: 10.1016/j.nbt.2021.05.004. Epub 2021 May 29. PMID: 34058397.
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Targeted mutagenesis in plants using Beet curly top virus for efficient delivery of CRISPR/Cas12a components.

New biotechnology

Eini O, Schumann N, Niessen M, Varrelmann M.
PMID: 34896246
N Biotechnol. 2021 Dec 08;67:1-11. doi: 10.1016/j.nbt.2021.12.002. Epub 2021 Dec 08.

Genome editing using CRISPR/Cas is rapidly being developed for gene targeting in eukaryotes including plants. However, gene targeting by homology-directed DNA recombination (HDR) is an infrequent event compared to the dominant DNA repair by non-homologous end-joining. Another bottleneck is...

Cite
Eini O, Schumann N, Niessen M, et al. Targeted mutagenesis in plants using Beet curly top virus for efficient delivery of CRISPR/Cas12a components. N Biotechnol. 2021;67:1-11doi: 10.1016/j.nbt.2021.12.002.
Eini, O., Schumann, N., Niessen, M., & Varrelmann, M. (2021). Targeted mutagenesis in plants using Beet curly top virus for efficient delivery of CRISPR/Cas12a components. New biotechnology, 671-11. https://doi.org/10.1016/j.nbt.2021.12.002
Eini, Omid, et al. "Targeted mutagenesis in plants using Beet curly top virus for efficient delivery of CRISPR/Cas12a components." New biotechnology vol. 67 (2021): 1-11. doi: https://doi.org/10.1016/j.nbt.2021.12.002
Eini O, Schumann N, Niessen M, Varrelmann M. Targeted mutagenesis in plants using Beet curly top virus for efficient delivery of CRISPR/Cas12a components. N Biotechnol. 2021 Dec 08;67:1-11. doi: 10.1016/j.nbt.2021.12.002. Epub 2021 Dec 08. PMID: 34896246.
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Next biotechnological plants for addressing global challenges: The contribution of transgenesis and new breeding techniques.

New biotechnology

Ricroch AE, Martin-Laffon J, Rault B, Pallares VC, Kuntz M.
PMID: 34537403
N Biotechnol. 2021 Sep 16;66:25-35. doi: 10.1016/j.nbt.2021.09.001. Epub 2021 Sep 16.

The aim of this survey is to identify and characterize new products in plant biotechnology since 2015, especially in relation to the advent of New Breeding Techniques (NBTs) such as gene editing based on the CRISPR-Cas system. Transgenic (gene...

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Ricroch AE, Martin-Laffon J, Rault B, et al. Next biotechnological plants for addressing global challenges: The contribution of transgenesis and new breeding techniques. N Biotechnol. 2021;66:25-35doi: 10.1016/j.nbt.2021.09.001.
Ricroch, A. E., Martin-Laffon, J., Rault, B., Pallares, V. C., & Kuntz, M. (2021). Next biotechnological plants for addressing global challenges: The contribution of transgenesis and new breeding techniques. New biotechnology, 6625-35. https://doi.org/10.1016/j.nbt.2021.09.001
Ricroch, Agnès E, et al. "Next biotechnological plants for addressing global challenges: The contribution of transgenesis and new breeding techniques." New biotechnology vol. 66 (2021): 25-35. doi: https://doi.org/10.1016/j.nbt.2021.09.001
Ricroch AE, Martin-Laffon J, Rault B, Pallares VC, Kuntz M. Next biotechnological plants for addressing global challenges: The contribution of transgenesis and new breeding techniques. N Biotechnol. 2021 Sep 16;66:25-35. doi: 10.1016/j.nbt.2021.09.001. Epub 2021 Sep 16. PMID: 34537403.
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